Endogenous gamma interferon is essential in granuloma formation induced by glycolipid-containing mycolic acid in mice.

@article{Asano1993EndogenousGI,
  title={Endogenous gamma interferon is essential in granuloma formation induced by glycolipid-containing mycolic acid in mice.},
  author={M. Asano and A. Nakane and T. Minagawa},
  journal={Infection and immunity},
  year={1993},
  volume={61 7},
  pages={
          2872-8
        }
}
  • M. Asano, A. Nakane, T. Minagawa
  • Published 1993
  • Biology, Medicine
  • Infection and immunity
  • The present study examined the role of endogenous gamma interferon (IFN-gamma) in the formation of granulomas in mice which had been given a single intravenous injection of glycolipid-containing mycolic acid (trehalose 2,3,6'-trimycolate) purified from cell walls of Rhodococcus aurantiacus (Gordona aurantiaca) (GaGM) in the form of liposome. The histological status of granuloma formation in the livers, spleens, and lungs of GaGM-injected mice was studied at weeks 1 through 5, and the titers of… CONTINUE READING
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