Endogenous galectin-1 exerts tonic inhibition on experimental arthritis.


Little is known about the role(s) of endogenous galectin-1 (Gal-1) in arthritis. In this study we queried whether antiarthritic functions for this effector of endogenous anti-inflammation could be unveiled by studying collagen-induced arthritis in Gal-1(-/-) mice. Gal-1(-/-) and C57BL/6J [wild-type (WT)] mice received an immunization of chicken type II… (More)
DOI: 10.4049/jimmunol.1203291


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@article{Iqbal2013EndogenousGE, title={Endogenous galectin-1 exerts tonic inhibition on experimental arthritis.}, author={Asif J Iqbal and Dianne Cooper and Alexander Vugler and Beatrice R Gittens and Adrian Moore and Mauro Perretti}, journal={Journal of immunology}, year={2013}, volume={191 1}, pages={171-7} }