Endogenous estradiol and progesterone concentrations in smokers on oral contraceptives.

Abstract

The simultaneous effects of cigarette smoking and oral contraceptives on serum estradiol and progesterone levels were investigated in 114 premenopausal women. Serum 17 beta-estradiol and progesterone levels were measured by radioimmunoassay. In smokers, estradiol and progesterone levels were significantly lower (p less than 0.025). In smokers using oral contraceptives, estradiol and progesterone levels were the lowest (p less than 0.001 and p less than 0.01, respectively). The findings suggest that smoking and oral contraceptives independently lower serum estradiol and progesterone concentrations in premenopausal women and that the effects may be additive.

Cite this paper

@article{Basu1992EndogenousEA, title={Endogenous estradiol and progesterone concentrations in smokers on oral contraceptives.}, author={Jayasri Basu and Magdy S. Mikhail and Prabhudas R. Palan and Benjamin Thysen and Eric Bloch and S L Romney}, journal={Gynecologic and obstetric investigation}, year={1992}, volume={33 4}, pages={224-7} }