Endogenous endothelin in human coronary vascular function: differential contribution of endothelin receptor types A and B.

@article{Halcox2007EndogenousEI,
  title={Endogenous endothelin in human coronary vascular function: differential contribution of endothelin receptor types A and B.},
  author={Julian P. J. Halcox and K. A. Nour and Gloria Zalos and Arshed A Quyyumi},
  journal={Hypertension},
  year={2007},
  volume={49 5},
  pages={1134-41}
}
Endothelin 1 mediates coronary vasoconstriction and endothelial dysfunction via endothelin receptor type A (ET(A)) activation. However, the effects of selective endothelin receptor type B (ET(B)) and combined ET(A+B) receptor blockade on coronary vasomotion are unknown. We measured coronary vascular tone and endothelium-dependent and -independent vasomotor function before and after selective infusion of BQ-788 (an ET(B) receptor antagonist) or combined infusion of BQ-788+BQ-123 (an ET(A… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Coronary microvascular dysfunction after long-term diabetes and hypercholesterolemia.

American journal of physiology. Heart and circulatory physiology • 2016
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…