Endogenous digoxin-like immunoreactive factor (DLIF) serum concentrations are decreased in manic bipolar patients compared to normal controls.

@article{Grider1999EndogenousDI,
  title={Endogenous digoxin-like immunoreactive factor (DLIF) serum concentrations are decreased in manic bipolar patients compared to normal controls.},
  author={Glenna Grider and Rif S. El-Mallakh and Mary O'Malley Huff and Teresa Buss and Jill Miller and Roland Valdes},
  journal={Journal of affective disorders},
  year={1999},
  volume={54 3},
  pages={261-7}
}
BACKGROUND A decrease in sodium pump activity in erythrocytes has been associated with manic episodes of bipolar illness relative to euthymic moods. Since red blood cells are long-lived and lack a nucleus, it is likely that a plasma factor is responsible for the observed decrease in sodium pump activity. METHODS Utilizing a radioimmunoassay, we examined the serum concentrations of the digoxin-like immunoreactive factor (DLIF) in ill and well bipolar patients and compared the values to those… CONTINUE READING

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