Endogenous cortisol level interacts with noradrenergic activation in the human amygdala.

  title={Endogenous cortisol level interacts with noradrenergic activation in the human amygdala.},
  author={Anda H van Stegeren and Oliver T. Wolf and W. Th. A. M. Everaerd and Philip Scheltens and Frederik Barkhof and Serge A. R. B. Rombouts},
  journal={Neurobiology of learning and memory},
  volume={87 1},
Animal studies show that high cortisol levels exert their effect on stressful task performance via modulation of the amygdala. Availability of noradrenaline in this brain region appears to be a critical prerequisite for this effect. This relationship between noradrenaline and cortisol is explained by an animal model where the amygdala constitutes a crucial region for this interaction. In humans this model has not been extensively tested so far. In a previously reported study human subjects… CONTINUE READING
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