Endogenous circulating ghrelin does not mediate growth hormone rhythmicity or response to fasting.

@article{Avram2005EndogenousCG,
  title={Endogenous circulating ghrelin does not mediate growth hormone rhythmicity or response to fasting.},
  author={Anca Avram and Craig A. Jaffe and Kathleen V Symons and Ariel L Barkan},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 5},
  pages={2982-7}
}
GH secretory profiles in humans are pulsatile and exhibit nocturnal elevation during the early hours of sleep. Fasting augments GH output and rhythmicity. Ghrelin was suggested to exhibit nocturnal increases and to rise in response to nutritional deprivation. We examined whether ghrelin may be an underlying mechanism of GH rhythmicity and response to fasting. We studied nine young healthy subjects during normal feeding and after 2 d of complete fasting. Plasma GH was measured every 10 min, and… CONTINUE READING