Endogenous circadian rhythm in an index of cardiac vulnerability independent of changes in behavior.

@article{Hu2004EndogenousCR,
  title={Endogenous circadian rhythm in an index of cardiac vulnerability independent of changes in behavior.},
  author={Kun Hu and Plamen Ch. Ivanov and Michael F. Hilton and Zhi He Chen and R Timothy Ayers and H. Eugene Stanley and Steven Andrew Shea},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 52},
  pages={18223-7}
}
There exists a robust day/night pattern in the incidence of adverse cardiac events with a peak at approximately 10 a.m. This peak traditionally has been attributed to day/night patterns in behaviors affecting cardiac function in vulnerable individuals. However, influences from the endogenous circadian pacemaker independent from behaviors may also affect cardiac control. Heartbeat dynamics under healthy conditions exhibit robust complex fluctuations characterized by self-similar temporal… CONTINUE READING