Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis

@inproceedings{Guo2015EndogenousCM,
  title={Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis},
  author={Shi-bin Guo and Zhijun Duan and Qiu-ming Wang and Qin Zhou and Qing Li and Xiao-yu Sun},
  booktitle={Experimental and therapeutic medicine},
  year={2015}
}
The aim of the present study was to investigate the effect of endogenous carbon monoxide (CO) on the hydrogen sulfide/cystathionine-γ-lyase (H2S/CSE) pathway in cirrhotic rat livers. The rats were allocated at random into four groups: Sham, cirrhosis, cobalt protoporphyrin (CoPP) and zinc protoporphyrin IX (ZnPP). The expression of hepatic CSE mRNA was… CONTINUE READING