Endogenous biosynthesis of prostacyclin during cardiac catheterization and angiography in man.

@article{Roy1985EndogenousBO,
  title={Endogenous biosynthesis of prostacyclin during cardiac catheterization and angiography in man.},
  author={Louise Roy and H. Knapp and Rose Marie Robertson and Garret A. FitzGerald},
  journal={Circulation},
  year={1985},
  volume={71 3},
  pages={
          434-40
        }
}
The potent platelet inhibitory and vasodilator properties of prostacyclin suggest that levels of this substance may be of relevance to drug action and pathologic processes in the coronary vascular bed. Attempts to estimate the coronary secretion rate of prostacyclin have relied on measurements of metabolites obtained via cardiac catheter, usually as an adjunct to coronary angiography. To test the hypothesis that such procedures might themselves perturb endogenous biosynthesis of prostacyclin we… CONTINUE READING
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