Endogenous beta-adrenergic receptors inhibit lipopolysaccharide-induced pulmonary cytokine release and coagulation.

@article{Giebelen2008EndogenousBR,
  title={Endogenous beta-adrenergic receptors inhibit lipopolysaccharide-induced pulmonary cytokine release and coagulation.},
  author={Ida A. J. Giebelen and Masja Leendertse and Mark C Dessing and Joost C M Meijers and Marcel Levi and Christian Draing and Sonja von Aulock and Tom van der Poll},
  journal={American journal of respiratory cell and molecular biology},
  year={2008},
  volume={39 3},
  pages={373-9}
}
Beta2-adrenergic receptors are expressed on different cell types in the lung, including respiratory epithelial cells, smooth muscle cells, and macrophages. The aim of the current study was to determine the role of beta-adrenergic receptors in the regulation of lung inflammation induced by instillation via the airways of lipopolysaccharide (LPS) (a constituent of the gram-negative bacterial cell wall) or lipoteichoic acid (LTA) (a component of the gram-positive bacterial cell wall). Mice inhaled… CONTINUE READING

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