Endogenous GM-CSF is involved as an autocrine growth factor for human osteoblastic cells

@inproceedings{Modrowski1997EndogenousGI,
  title={Endogenous GM-CSF is involved as an autocrine growth factor for human osteoblastic cells},
  author={Dominique Modrowski and Abderrahim Lomri and Pierre Jacques Marie},
  year={1997}
}
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important modulator of hematopoietic cells. However, the role of GM-CSF in nonhematopoietic cells remains unclear. We have determined whether GM-CSF is an autocrine mitogenic factor for human osteoblastic (hOB) cells. We found by reverse transcriptase-polymerase chain reaction (RT-PCR) that hOB cells express constitutively both GM-CSF and the α and β chains of the GM-CSF receptor (GMR). Immunocytochemistry showed that serum-starved… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Integrins, Oncogenes, and Anchorage Independence

  • The Journal of cell biology
  • 1997
VIEW 1 EXCERPT
CITES BACKGROUND

Similar Papers