Endogenous Digitalis-Like Factors: An Overview of the History

@inproceedings{Buckalew2015EndogenousDF,
  title={Endogenous Digitalis-Like Factors: An Overview of the History},
  author={Vardaman M. Buckalew},
  booktitle={Front. Endocrinol.},
  year={2015}
}
The sodium pump is a ubiquitous cell surface enzyme, a Na, K ATPase, which maintains ion gradients between cells and the extracellular fluid (ECF). The extracellular domain of this enzyme contains a highly conserved binding site, a receptor for a plant derived family of compounds, the digitalis glycosides. These compounds inhibit the enzyme and are used in… CONTINUE READING