Endogenous BMPR-IB signaling is required for early osteoblast differentiation of human bone cells


Osteoblast differentiation is tightly regulated by a number of cytokines and growth factors, including bone morphogenetic proteins (BMP) which stimulate osteoblast differentiation by signal transduction via three BMP receptors (BMPR-IA, -IB and -II). Although the mechanisms which regulate osteoblast differentiation are not fully understood, it is possible… (More)
DOI: 10.1007/s11626-010-9378-z


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