Endofungal bacterium controls its host by an hrp type III secretion system

  title={Endofungal bacterium controls its host by an hrp type III secretion system},
  author={Gerald Lackner and Nadine Moebius and Christian Hertweck},
  journal={The ISME Journal},
Burkholderia rhizoxinica and Rhizopus microsporus form a unique symbiosis in which intracellular bacteria produce the virulence factor of the phytopathogenic fungus. Notably, the host strictly requires endobacteria to sporulate. In this study, we show that the endofungal bacteria possess a type III secretion system (T3SS), which has a crucial role in the maintenance of the alliance. Mutants defective in type III secretion show reduced intracellular survival and fail to elicit sporulation of the… CONTINUE READING
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