Endodontic medicine: connections between apical periodontitis and systemic diseases.

@article{SeguraEgea2015EndodonticMC,
  title={Endodontic medicine: connections between apical periodontitis and systemic diseases.},
  author={Juan Jos{\'e} Segura-Egea and Jenifer Mart{\'i}n-Gonz{\'a}lez and Lissett Castellanos-Cosano},
  journal={International endodontic journal},
  year={2015},
  volume={48 10},
  pages={
          933-51
        }
}
The prevalence of apical periodontitis (AP) in Europe has been reported to affect 61% of individuals and 14% of teeth, and increase with age. Likewise, the prevalence of root canal treatment (RCT) in Europe is estimated to be around 30-50% of individuals and 2-9% of teeth with radiographic evidence of chronic persistent AP in 30-65% of root filled teeth (RFT). AP is not only a local phenomenon and for some time the medical and dental scientific community have analysed the possible connection… 

Figures and Tables from this paper

Relationship between periodontal and endodontic diseases and systemic health: correlation does not imply causation.

There is an association between periodontal or periapical inflammatory diseases and some systemic pathologies, without being able to assert definitively, based on scientific evidence, that there is a causal link between them.

Prevalence of Apical Periodontitis in patients with Multiple Myeloma

The presence of AP and endodontic treatment was not significantly different in individuals with MM compared with control subjects, and future studies are needed to elucidate and confirm the association between MM and AP.

Apical periodontitis in southern Estonian population: prevalence and associations with quality of root canal fillings and coronal restorations

AP is highly prevalent in Southern Estonian population and most cases are associated with root canal-treated teeth, consistent with the mediocre outcome of treatment.

Impact of Endodontically Treated Teeth on Systemic Diseases

It was found that 42.5% of the group with systemic diseases showed immunological disturbance as a result of root-filled teeth, and the presence of AP was almost three times higher than in the control group.

Prevalence of endodontic infection in patients with Crohn´s disease and ulcerative colitis

The results of the present study show similar frequency of AP and RFT in both UC and CD patients, and the type of IBD does not appear to affect the prevalence of radiographically detectable periapical lesions or the popularity of root canal treatment.

Association between Endodontic Infection, Its Treatment and Systemic Health: A Narrative Review

Convincing evidence supports that successful root canal treatment has a beneficial impact on systemic health by reducing the inflammatory burden, thereby dismissing the misconceptions of focal infection theory.

Apical periodontitis associates with cardiovascular diseases

The results confirmed the hypothesis by showing that AP statistically associated with cardiovascular diseases and the finding that subjects with AP also often had periodontitis indicates an increased oral inflammatory burden.

High Prevalence of Apical Periodontitis in Patients With Inflammatory Bowel Disease: An Age- and Gender- matched Case-control Study.

Subjects with inflammatory bowel disease have higher prevalence of apical periodontitis, and an oral health protocol should be established to address theHigher prevalence of inflammatory oral processes.

The prevalence of apical periodontitis and endodontic treatment in two coagulation disorders

The coagulation disorders evaluated here did not influence the manifestation of AP, however, they affected the inflammatory responses and tissue repair mechanisms.
...

References

SHOWING 1-10 OF 162 REFERENCES

Diabetes mellitus, periapical inflammation and endodontic treatment outcome

It is concluded that there are data in the literature that associate DM with a higher prevalence of periapical lesions, greater size of the osteolityc lesions, great likelihood of asymptomatic infections and worse prognosis for root filled teeth.

High prevalence of radiolucent periapical lesions amongst patients with inherited coagulation disorders

Patients with I CD disorders showed a significantly higher prevalence of RPL and lower frequency of RCT than control patients, and subjects with ICD had RPL with higher likelihood than control subjects.

Prevalence of apical periodontitis and frequency of root canal treatments in liver transplant candidates

Liver transplant candidates have significantly higher prevalence of radiographic periapical lesions and lower frequency of RFT than controls healthy subjects.

Prevalence of apical periodontitis and frequency of root-filled teeth in an adult Spanish population.

The prevalence ofRoot-filled teeth with AP was found to be higher compared to that demonstrated in other epidemiological studies, and the frequency of root- filled teeth were comparable to those reported in previous similar studies carried out in European countries.

Hypertension and dental periapical condition.

Tobacco smoking and dental periapical condition.

Investigating whether tobacco smoking might be associated with the prevalence or severity of periapical lesions concluded that the present observations do not lend support to the assumption that tobacco smoking is associated with apical periodontitis.

Relationship between smoking and endodontic variables in hypertensive patients.

Frequency and distribution of root-filled teeth and apical periodontitis in an adult population of Barcelona, Spain.

Both the prevalence of AP and the frequency of root canal treatment are high among Spanish adults and patients with one or more RFT have a greater likelihood of having AP than patients without RFT.

Apical periodontitis and cardiovascular diseases: previous findings and ongoing research.

Preventive measures for IE should be adopted during endodontic treatment of patients at risk for cardiovascular events according to the American and European available official guidelines, and more research focused on apical periodontitis and systemic diseases is needed.
...