Endodontic antimicrobial photodynamic therapy: safety assessment in mammalian cell cultures.

@article{Xu2009EndodonticAP,
  title={Endodontic antimicrobial photodynamic therapy: safety assessment in mammalian cell cultures.},
  author={Yan Xu and Mark J. Young and Ricardo A. Battaglino and Leslie R. Morse and Carla Raquel Fontana and T. Pagonis and Ralph Kent and Nikolaos S. Soukos},
  journal={Journal of endodontics},
  year={2009},
  volume={35 11},
  pages={1567-72}
}
OBJECTIVES The purpose of this study was to assess the in vitro synergistic effect of methylene blue (MB) and red light on human gingival fibroblasts and osteoblasts with parameters similar to those that may be applied in a clinical setting for endodontic disinfection. MATERIALS AND METHODS Both cell types were sensitized with 50 microg/mL MB followed by exposure to red light at 665 nm for 5 minutes with an irradiance of 10, 20, and 40 mW/cm(2). After photodynamic therapy (PDT), cell… CONTINUE READING