Endocytosis of the Mu Opioid Receptor Reduces Tolerance and a Cellular Hallmark of Opiate Withdrawal

@article{Finn2001EndocytosisOT,
  title={Endocytosis of the Mu Opioid Receptor Reduces Tolerance and a Cellular Hallmark of Opiate Withdrawal},
  author={Andrew Finn and Jennifer L. Whistler},
  journal={Neuron},
  year={2001},
  volume={32},
  pages={829-839}
}

Figures from this paper

Role of receptor internalization in opioid tolerance and dependence.

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Morphine induces endocytosis of neuronal μ-opioid receptors through the sustained transfer of Gα subunits to RGSZ2 proteins

TLDR
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Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance

TLDR
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...

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