Endocytosis by antigen presenting cells: dendritic cells are as endocytically active as other antigen presenting cells.

@article{Levine1992EndocytosisBA,
  title={Endocytosis by antigen presenting cells: dendritic cells are as endocytically active as other antigen presenting cells.},
  author={Timothy P. Levine and Benjamin M. Chain},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 17},
  pages={8342-6}
}
Although dendritic cells are the most potent of all antigen presenting cells, they have paradoxically been regarded as having only a minimal capacity for endocytosis, which is a crucial step in antigen processing prior to presentation. Previous studies of dendritic cells, which are only available in small numbers, have been restricted to measurement of long-term endocytosis and so have stressed lysosomal accumulation. Measurement of traffic through late endosomes, which are closely related to… CONTINUE READING

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