Endocytic transport of integrins during cell migration and invasion.

@article{Caswell2008EndocyticTO,
  title={Endocytic transport of integrins during cell migration and invasion.},
  author={Patrick T. Caswell and Jim C Norman},
  journal={Trends in cell biology},
  year={2008},
  volume={18 6},
  pages={257-63}
}
Early studies describing the endocytic-exocytic cycling of integrins prompted proposals that this process regulates cell migration. However, it is only relatively recently that more detailed descriptions of the molecular machinery responsible for directing integrin trafficking have enabled us to properly address the role of these events during the various modes of cell migration. Here, we review recent advances in our understanding of the protein complexes and signallosomes controlling integrin… CONTINUE READING

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alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration

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  • J. Cell Biol
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