Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury.

@article{Mori2005EndocyticDO,
  title={Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury.},
  author={Kiyoshi Mori and Heewon Lee and Dana Rapoport and Ian R. Drexler and Kirk Foster and Jun Yang and Kai M Schmidt-Ott and Xia Chen and Jau Yi Li and Stacey F Weiss and Jaya Mishra and Faisal Habib Cheema and Glenn Markowitz and Takayoshi Suganami and Kazutomo Sawai and Masashi Mukoyama and Cheryl L Kunis and Vivette D D'agati and Prasad Devarajan and Jonathan Barasch},
  journal={The Journal of clinical investigation},
  year={2005},
  volume={115 3},
  pages={610-21}
}
Neutrophil gelatinase-associated lipocalin (Ngal), also known as siderocalin, forms a complex with iron-binding siderophores (Ngal:siderophore:Fe). This complex converts renal progenitors into epithelial tubules. In this study, we tested the hypothesis that Ngal:siderophore:Fe protects adult kidney epithelial cells or accelerates their recovery from damage… CONTINUE READING