Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis.

Abstract

Fibrosis of the liver and its end-stage, cirrhosis, represent major health problems worldwide. In these fibrotic conditions, activated fibroblasts and hepatic stellate cells display a net deposition of collagen. This collagen deposition is a major factor leading to liver dysfunction, thus making it crucially important to understand both the collagen… (More)
DOI: 10.1002/path.3981

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