Endocrine tumors of the cervix: morphologic assessment, expression of human papillomavirus, and evaluation for loss of heterozygosity on 1p,3p, 11q, and 17p.

@article{Mannion1998EndocrineTO,
  title={Endocrine tumors of the cervix: morphologic assessment, expression of human papillomavirus, and evaluation for loss of heterozygosity on 1p,3p, 11q, and 17p.},
  author={C. L. T. Mannion and Weon Seo Park and Yan Gao Man and Zhengping Zhuang and Jorge Albores-Saavedra and Fattaneh A. Tavassoli},
  journal={Cancer},
  year={1998},
  volume={83 7},
  pages={1391-400}
}
BACKGROUND Cervical endocrine tumors are rare lesions, with a varied diagnostic nomenclature. A recent consensus meeting proposed a standardized terminology. This study evaluated: 1) applicability of histopathologic guidelines; 2) evidence of loss of heterozygosity (LOH) at selected sites; and 3) the presence of human papillomavirus (HPV) detected by nonisotopic in situ hybridization (ISH). METHODS Thirty-eight cases (patient age range, 19-88 years; mean, 48 years) were retrieved. Outcome… CONTINUE READING