Endocrine status in patients with optic nerve hypoplasia: relationship to midline central nervous system abnormalities and appearance of the hypothalamic-pituitary axis on magnetic resonance imaging.

@article{Birkebaek2003EndocrineSI,
  title={Endocrine status in patients with optic nerve hypoplasia: relationship to midline central nervous system abnormalities and appearance of the hypothalamic-pituitary axis on magnetic resonance imaging.},
  author={Niels H Birkebaek and Lisa G Patel and Neville Bryce Wright and John R Grigg and Smeeta Sinha and Catherine Margaret Hall and David Anthony Price and Ian Lloyd and Peter E Clayton},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2003},
  volume={88 11},
  pages={5281-6}
}
We here: 1) describe the phenotypic spectrum, including magnetic resonance imaging (MRI) appearances of the pituitary stalk and anterior and posterior pituitary [H-P (hypothalamic-pituitary) axis], in children with optic nerve hypoplasia (ONH) with or without an abnormal septum pellucidum (SP); and 2) define endocrine dysfunction according to the MRI findings. Medical records of 55 children with ONH who had been assessed by ophthalmology and endocrine services were reviewed. All had MRI of the… CONTINUE READING
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