Endocrine response determines the clinical outcome of pulsatile gonadotropin-releasing hormone ovulation induction in different ovulatory disorders.

@article{Filicori1991EndocrineRD,
  title={Endocrine response determines the clinical outcome of pulsatile gonadotropin-releasing hormone ovulation induction in different ovulatory disorders.},
  author={Marco Filicori and Carlo Flamigni and Maria C Meriggiola and Paolo Ferrari and L Michelacci and E Campaniello and A Valdiserri and Graçiela Estela Cognigni},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1991},
  volume={72 5},
  pages={965-72}
}
To accrue systematic information in different ovulatory disorders on the precise relationship among endocrine response, clinical outcome, and the occurrence of complications, we treated 114 patients with pulsatile GnRH (2.5-5.0 micrograms, iv, every 60 min) for 187 cycles and compared them to 20 normal menstrual cycles. Thirty of these patients had primary hypogonadotropic amenorrhea (PHA; 40 cycles), 33 had other forms of hypogonadotropic hypogonadism (HH; 55 cycles), and 51 had polycystic… CONTINUE READING