Endocrine regulation of HOX genes.

  title={Endocrine regulation of HOX genes.},
  author={Gaurang S. Daftary and Hugh S. Taylor},
  journal={Endocrine reviews},
  volume={27 4},
Hox genes have a well-characterized role in embryonic development, where they determine identity along the anteroposterior body axis. Hox genes are expressed not only during embryogenesis but also in the adult, where they are necessary for functional differentiation. Despite the known function of these genes as transcription factors, few regulatory mechanisms that drive Hox expression are known. Recently, several hormones and their cognate receptors have been shown to regulate Hox gene… CONTINUE READING
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