Endocrine hormones and local signals during the development of the mouse mammary gland.

@article{Brisken2015EndocrineHA,
  title={Endocrine hormones and local signals during the development of the mouse mammary gland.},
  author={Cathrin Brisken and Dalya Ataca},
  journal={Wiley interdisciplinary reviews. Developmental biology},
  year={2015},
  volume={4 3},
  pages={181-95}
}
Most of mammary gland development occurs postnatally under the control of female reproductive hormones, which in turn interact with other endocrine factors. While hormones impinge on many tissues and trigger very complex biological responses, tissue recombination experiments with hormone receptor-deficient mammary epithelia revealed eminent roles for estrogens, progesterone, and prolactin receptor (PrlR) signaling that are intrinsic to the mammary epithelium. A subset of the luminal mammary… CONTINUE READING
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