Endocrine effects of adjuvant letrozole compared with tamoxifen in hormone-responsive postmenopausal patients with early breast cancer: the HOBOE trial.

@article{Rossi2009EndocrineEO,
  title={Endocrine effects of adjuvant letrozole compared with tamoxifen in hormone-responsive postmenopausal patients with early breast cancer: the HOBOE trial.},
  author={Emanuela Rossi and Alessandro Morabito and Francesca Di Rella and Giuseppe Esposito and Adriano Gravina and Vincenzo Labonia and Gabriella Landi and Francesco Nuzzo and Carmen Pacilio and Ermelinda De Maio and Massimo Di Maio and Maria Carmela Piccirillo and Gianfranco de Feo and G D'aiuto and Gerardo Botti and Paolo Chiodini and Ciro Gallo and Francesco Perrone and Andrea de Matteis},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2009},
  volume={27 19},
  pages={3192-7}
}
PURPOSE We compared the endocrine effects of 6 and 12 months of adjuvant letrozole versus tamoxifen in postmenopausal patients with hormone-responsive early breast cancer within an ongoing phase III trial. PATIENTS AND METHODS Patients were randomly assigned to receive tamoxifen, letrozole, or letrozole plus zoledronic acid. Serum values of estradiol, follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, dehydroepiandrosterone-sulphate (DHEA-S), progesterone, and cortisol… CONTINUE READING
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Endocrine effects of adjuvant letrozole plus triptorelin versus tamoxifen plus triptorelin in premenopausal patients with early breast cancer

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15 - year survival : An overview of the randomized trials

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