Endocrine disruptors in the etiology of type 2 diabetes mellitus

@article{AlonsoMagdalena2011EndocrineDI,
  title={Endocrine disruptors in the etiology of type 2 diabetes mellitus},
  author={Paloma Alonso-Magdalena and Iv{\'a}n Quesada and Angel Nadal},
  journal={Nature Reviews Endocrinology},
  year={2011},
  volume={7},
  pages={346-353}
}
The etiology of type 2 diabetes mellitus involves the induction of insulin resistance along with the disruption of pancreatic β-cell function and the loss of β-cell mass. In addition to a genetic predisposition, lifestyle factors seem to have an important role. Epidemiological studies indicate that the increased presence of endocrine disrupting chemicals (EDCs) in the environment may also play an important part in the incidence of metabolic diseases. Widespread EDCs, such as dioxins, pesticides… 
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