Endocrine disruption in adolescence: immunologic, hematologic, and bone effects in monkeys.

@article{Golub2004EndocrineDI,
  title={Endocrine disruption in adolescence: immunologic, hematologic, and bone effects in monkeys.},
  author={M. Golub and Casey E. Hogrefe and Stacey L. Germann and Christopher P. Jerome},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2004},
  volume={82 2},
  pages={598-607}
}
Environmental contaminants with estrogenic properties have the potential to alter pubertal development. In addition to the reproductive system, other systems that mature under the influence of estrogen could be affected. This study examined the effect on immune, hematologic, and bone mass parameters of treatment with estrogenic agents (methoxychlor, MXC, 25 and 50 mg/kg/day; diethylstilbestrol, DES, 0.5 mg/kg/day) given in the peripubertal period to female rhesus monkeys. DES had striking… CONTINUE READING