Endocrine complications of pediatric stem cell transplantation.

  title={Endocrine complications of pediatric stem cell transplantation.},
  author={Charles A. Sklar and Farid Boulad and Trudy N. Small and Nancy A Kernan},
  journal={Frontiers in bioscience : a journal and virtual library},
Abnormalities of endocrine function and growth are common following stem cell transplantation in the pediatric/adolescent population. Impaired linear growth and adult short stature are associated with younger age at transplant, use of TBI and prior cranial irradiation, and development of chronic GvHD. Primary hypothyroidism is the most common abnormality of the thyroid and is observed in 10-28% of cases following fractionated TBI. Autoimmune hyperthyroidism has also been described post-stem… CONTINUE READING


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