Endocrine biomarkers and symptom clusters during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study.

@article{Woods2014EndocrineBA,
  title={Endocrine biomarkers and symptom clusters during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study.},
  author={Nancy Fugate Woods and Lori A Cray and Ellen Sullivan Mitchell and Jerald R. Herting},
  journal={Menopause},
  year={2014},
  volume={21 6},
  pages={646-52}
}
OBJECTIVE During the menopausal transition and early postmenopause, participants in the Seattle Midlife Women's Health Study were likely to belong to one of three symptom severity classes: severe hot flashes with moderate sleep, mood, cognitive, and pain symptoms (high-severity hot flash); moderate levels of all but hot flashes (moderate severity); and low levels of all (low severity). We tested models of the differential effects of hypothalamic-pituitary-ovarian (HPO) axis, hypothalamic… CONTINUE READING