Endocrine and inflammatory markers as predictors of frailty.

@article{Puts2005EndocrineAI,
  title={Endocrine and inflammatory markers as predictors of frailty.},
  author={Martine T. E. Puts and Marjolein Visser and Jos W. R. Twisk and Dorly J H Deeg and P J A Lips},
  journal={Clinical endocrinology},
  year={2005},
  volume={63 4},
  pages={
          403-11
        }
}
OBJECTIVE To examine the association of serum concentrations of 25-hydroxyvitamin D [25(OH)D], interleukin-6 (IL-6), C-reactive protein (CRP) and IGF-1 with prevalent and incident frailty. DESIGN The Longitudinal Aging Study Amsterdam (LASA), a prospective cohort study with 3-yearly measurement cycles. Setting General population-based sample. PARTICIPANTS The respondents were men and women aged 65 and over, who participated at T1 (1995/1996, N = 1720) and T2 (1998/1999, N = 1509). Blood… CONTINUE READING

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