Endocrine Regulation of Energy Metabolism by the Skeleton

Abstract

The regulation of bone remodeling by an adipocyte-derived hormone implies that bone may exert a feedback control of energy homeostasis. To test this hypothesis we looked for genes expressed in osteoblasts, encoding signaling molecules and affecting energy metabolism. We show here that mice lacking the protein tyrosine phosphatase OST-PTP are hypoglycemic… (More)
DOI: 10.1016/j.cell.2007.05.047

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@article{Lee2007EndocrineRO, title={Endocrine Regulation of Energy Metabolism by the Skeleton}, author={Na Kyung Lee and Hideaki Sowa and Eiichi Hinoi and M. A. Vilches Ferr{\'o}n and Jong Deok Ahn and Cyrille B. Confavreux and Romain Dacquin and Patrick J. Mee and M D Mckee and Dae Young Jung and Zhiyou Zhang and Jason Kim and Franck Mauvais-Jarvis and Patricia Ducy and Gerard Karsenty}, journal={Cell}, year={2007}, volume={130}, pages={456-469} }