Endocardial Tip Cells in the Human Embryo – Facts and Hypotheses

  title={Endocardial Tip Cells in the Human Embryo – Facts and Hypotheses},
  author={Mugurel Constantin Rusu and Cristian Viorel Poalelungi and Alexandra Diana Vrapciu and Mihnea Ioan Nicolescu and Sorin Hostiuc and Laurențiu Mogoantă and Traian Ţăranu},
  booktitle={PloS one},
Experimental studies regarding coronary embryogenesis suggest that the endocardium is a source of endothelial cells for the myocardial networks. As this was not previously documented in human embryos, we aimed to study whether or not endothelial tip cells could be correlated with endocardial-dependent mechanisms of sprouting angiogenesis. Six human embryos (43-56 days) were obtained and processed in accordance with ethical regulations; immunohistochemistry was performed for CD105 (endoglin… CONTINUE READING
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