• DOI:10.1016/j.brainres.2008.09.019
Corpus ID: 26957176

Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia

@article{Schomacher2008EndocannabinoidsMN,
  title={Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia},
  author={M. Schomacher and H. M{\"u}ller and C. Sommer and S. Schwab and W. Sch{\"a}bitz},
  journal={Brain Research},
  year={2008},
  volume={1240},
  pages={213-220}
}

• M. Schomacher, H. Müller, +2 authors W. Schäbitz
• Published 2008
• Medicine
• Brain Research

The endocannabinoids anandamide (AEA) and palmitoylethanolamide (PEA) act as endogenous protective factors of the brain, using different pathways of neuroprotection against neuronal damage. Although several in vivo and in vitro studies confirmed the neuroprotective efficacy of endocannabinoids, no experimental settings compare and explore the neuroprotective potential of AEA and PEA in an acute stroke model. In this study, we investigated the neuroprotective potential by infarct measurement… Expand

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