Endocannabinoids link rapid, membrane-mediated corticosteroid actions to behavior.

  title={Endocannabinoids link rapid, membrane-mediated corticosteroid actions to behavior.},
  author={Robert J. Denver},
  volume={148 2},
  • R. Denver
  • Published 1 February 2007
  • Biology
  • Endocrinology
The rapid actions of steroid hormones, although recognized for over half a century, until recently were largely overshadowed by the study of genomic actions mediated by nuclear hormone receptors. Many steroid hormones are now known to exert physiologically and behaviorally important actions within seconds to minutes, a time frame far too rapid to be mediated by genomic mechanisms. The recent isolation of several G protein-coupled receptors (GPCRs) that mediate the actions of sex steroids and 1… 
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