Endocannabinoids in the treatment of mood disorders: evidence from animal models.

  title={Endocannabinoids in the treatment of mood disorders: evidence from animal models.},
  author={Francis Rodriguez Bambico and Andrea Duranti and Andrea Tontini and Giorgio Tarzia and Gabriella Gobbi},
  journal={Current pharmaceutical design},
  volume={15 14},
Among all mental disorders, major depression has the highest rate of prevalence and incidence of morbidity. Currently available antidepressant therapies have limited efficacies; consequently, research on new drugs for the treatment of mood disorders has become increasingly critical. Recent preclinical evidences that cannabinoid agonists and endocannabinoid enhancers, such as the fatty acid amide hydrolase (FAAH) inhibitors, can impact mood regulation have opened a new line of research in… CONTINUE READING
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