Endocannabinoids and related fatty acid amides, and their regulation, in the salivary glands of the lone star tick.

@article{Fezza2003EndocannabinoidsAR,
  title={Endocannabinoids and related fatty acid amides, and their regulation, in the salivary glands of the lone star tick.},
  author={Filomena Fezza and Jack W. Dillwith and Tiziana Bisogno and James S Tucker and Vincenzo Di Marzo and John R. Sauer},
  journal={Biochimica et biophysica acta},
  year={2003},
  volume={1633 1},
  pages={
          61-7
        }
}
The salivary glands and saliva from the lone star tick Amblyomma americanum (L.) were analyzed for the presence of the two endogenous agonists of cannabinoid receptors, N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG), as well as of the anandamide congener, N-palmitoylethanolamine (PEA), an anti-inflammatory and analgesic mediator that is inactive at cannabinoid receptors. Two very sensitive mass-spectrometric techniques were used for this purpose. Both 2-AG and PEA, as… CONTINUE READING

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