Endocannabinoid system involvement in brain reward processes related to drug abuse.

@article{Solinas2007EndocannabinoidSI,
  title={Endocannabinoid system involvement in brain reward processes related to drug abuse.},
  author={Marcello Solinas and Sevil Yasar and Steven R. Goldberg},
  journal={Pharmacological research},
  year={2007},
  volume={56 5},
  pages={393-405}
}
Cannabis is the most commonly abused illegal drug in the world and its main psychoactive ingredient, delta-9-tetrahydrocannabinol (THC), produces rewarding effects in humans and non-human primates. Over the last several decades, an endogenous system comprised of cannabinoid receptors, endogenous ligands for these receptors and enzymes responsible for the synthesis and degradation of these endogenous cannabinoid ligands has been discovered and partly characterized. Experimental findings strongly… CONTINUE READING

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