Endocannabinoid signaling in microglial cells

@article{Stella2009EndocannabinoidSI,
  title={Endocannabinoid signaling in microglial cells},
  author={Nephi Stella},
  journal={Neuropharmacology},
  year={2009},
  volume={56},
  pages={244-253}
}
The endocannabinoid signaling system (eCBSS) is composed of cannabinoid (CB) receptors, their endogenous ligands (the endocannabinoids, eCB) and the enzymes that produce and inactivate these ligands. Neurons use this signaling system to communicate with each other and Delta9-tetrahydrocannabinol (THC), the main psychotropic ingredient of Cannabis sativa, induces profound behavioral effects by impinging on this communication. Evidence now shows that microglia, the macrophages of the brain, also… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

Neuroinflammation in Huntington’s disease

Journal of Neural Transmission • 2010
View 4 Excerpts
Highly Influenced

Cannabinoids and glial cells: possible mechanism to understand schizophrenia

European Archives of Psychiatry and Clinical Neuroscience • 2018
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 147 references

Microglia Biology in Health and Disease

Journal of Neuroimmune Pharmacology • 2006
View 4 Excerpts
Highly Influenced

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.

Proceedings of the National Academy of Sciences of the United States of America • 1999
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…