Endocannabinoid regulation of relapse mechanisms.

  title={Endocannabinoid regulation of relapse mechanisms.},
  author={L Fattore and Paola Fadda and Walter Fratta},
  journal={Pharmacological research},
  volume={56 5},
Addiction involves a complex neuropharmacologic behavioural cycle, in which positive reinforcement exerted by the drug and the negative state of withdrawal drive the user to extremes to obtain the drug. Comprehensive studies have established that relapse is the most common outcome of recovery programs treating addictive behaviours. Several types of anticraving medication are available nowadays, such as naltrexone for the treatment of alcoholism, bupropion for nicotine, methadone or… CONTINUE READING

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