Endo-Porter: a novel reagent for safe, effective delivery of substances into cells.

@article{Summerton2005EndoPorterAN,
  title={Endo-Porter: a novel reagent for safe, effective delivery of substances into cells.},
  author={James E. Summerton},
  journal={Annals of the New York Academy of Sciences},
  year={2005},
  volume={1058},
  pages={62-75}
}
Delivering large molecules into the cytosol of animal cells without damaging the cells has been one of the toughest challenges in biology. Endo-Porter is a weak-base amphiphilic peptide that was designed to deliver morpholino antisense oligomers and other non-ionic substances into the cytosol/nuclear compartment of cells by an endocytosis-mediated process that avoids damaging the plasma membrane of the cell. This prevents the loss of vital cell contents and the attendant high cell toxicity… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Reverse signaling by glycosylphosphatidylinositol-linked Manduca ephrin requires a SRC family kinase to restrict neuronal migration in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2009
View 3 Excerpts
Highly Influenced

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1.

Proceedings of the National Academy of Sciences of the United States of America • 2015
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Similar Papers

Loading similar papers…