Endings in the middle: current knowledge of interstitial telomeric sequences.

@article{Lin2008EndingsIT,
  title={Endings in the middle: current knowledge of interstitial telomeric sequences.},
  author={Kah Wai Lin and Ju Yan},
  journal={Mutation research},
  year={2008},
  volume={658 1-2},
  pages={95-110}
}
Interstitial telomeric sequences (ITSs) consist of tandem repeats of the canonical telomeric repeat and are common in mammals. They are localized at intrachromosomal sites, including those repeats located close to the centromeres and those found at interstitial sites, i.e., between the centromeres and the telomeres. ITSs might originate from ancestral intrachromosomal rearrangements (inversions and fusions), from differential crossing-over or from the repair of double-strand break during… CONTINUE READING