Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis.

@article{Mas2006EndarterectomyVS,
  title={Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis.},
  author={J. Mas and G. Chatellier and B. Beyssen and A. Branchereau and T. Moulin and J. Becquemin and V. Larrue and M. Li{\`e}vre and D. Leys and J. Bonneville and J. Watelet and J. Pruvo and J. Albucher and A. Viguier and P. Piquet and P. Garnier and F. Viader and E. Touz{\'e} and M. Giroud and H. Hosseini and J. Pillet and P. Favrole and J. Neau and X. Ducrocq},
  journal={The New England journal of medicine},
  year={2006},
  volume={355 16},
  pages={
          1660-71
        }
}
BACKGROUND Carotid stenting is less invasive than endarterectomy, but it is unclear whether it is as safe in patients with symptomatic carotid-artery stenosis. METHODS We conducted a multicenter, randomized, noninferiority trial to compare stenting with endarterectomy in patients with a symptomatic carotid stenosis of at least 60%. The primary end point was the incidence of any stroke or death within 30 days after treatment. RESULTS The trial was stopped prematurely after the inclusion of… Expand
Safety of Stenting and Endarterectomy by Symptomatic Status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)
TLDR
For both CAS and CEA, stroke and death rates were below or comparable to those of previous randomized trials and were within the complication thresholds suggested in current guidelines for both symptomatic and asymptomatic patients. Expand
Long-term results of carotid stenting versus endarterectomy in high-risk patients.
TLDR
No significant difference could be shown in long-term outcomes between patients who underwent carotid artery stenting with an emboli-protection device and those who underwent endarterectomy. Expand
Long-Term Follow-Up Study of Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis Trial
TLDR
A difference driven by a lower risk of procedural stroke after endarterectomy was observed between treatment groups in the rates of ipsilateral stroke beyond the procedural period, severe carotid restenosis (≥70%) or occlusion, death, myocardial infarction, and revascularization procedures. Expand
Absence of Consistent Sex Differences in Outcomes From Symptomatic Carotid Endarterectomy and Stenting Randomized Trials.
TLDR
A pooled analysis among symptomatic patients in large randomized trials to provide more precise estimates of sex differences in the CAS-to-CEA risk for any stroke or death during the 120-day periprocedural period and ipsilateral stroke thereafter found significant differences between trials. Expand
Carotid stenting versus endarterectomy in the same patient: A “direct” comparison
TLDR
Carotid endarterectomy confirms its efficacy incarotid revascularization, but carotid artery stenting constitutes a good alternative when the procedures are selected based on patient-specific risk factors. Expand
Outcomes After Carotid Artery Stenting and Endarterectomy in the Medicare Population
TLDR
CAS patients had a similar stroke risk but an increased mortality rate at 1 year compared with CEA patients, possibly related to the higher baseline risk profile in the CAS patient group. Expand
The safety of carotid artery surgery and stenting
TLDR
Which baseline patient characteristics, processes of care or vascular anatomical variants are associated with risk of stroke, myocardial infarction (MI) or death within 30 days of either procedure, and whether existing models to predict the risk of these complications performed well in ICSS patients are determined. Expand
Factors Influencing Decision Making for Carotid Endarterectomy versus Stenting in the Very Elderly
TLDR
The aim of this review is to report the factors that may be responsible for the variability in the treatment of carotid stenosis, particularly in the elderly population, to integrate the current available evidence to individualize the treatment in this challenging population. Expand
[Internal carotid artery revascularization].
  • J. Mas
  • Medicine
  • Revista espanola de cardiologia
  • 2007
TLDR
Current data do not support the preferential use of carotid stenting overcarotid endarterectomy in patients with a symptomatic or asymptomatic carotids stenosis who are good candidates for surgery, and decision-making must take individual factors into consideration. Expand
Early Endarterectomy Carries a Lower Procedural Risk Than Early Stenting in Patients With Symptomatic Stenosis of the Internal Carotid Artery: Results From 4 Randomized Controlled Trials
TLDR
In randomized trials comparing stenting with CEA for symptomatic carotid artery stenosis, CAS was associated with a substantially higher periprocedural risk during the first 7 days after the onset of symptoms, suggesting early surgery is safer than stenting for preventing future stroke. Expand
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