End-product induced metabolic shifts in Clostridium thermocellum ATCC 27405

@article{Rydzak2011EndproductIM,
  title={End-product induced metabolic shifts in Clostridium thermocellum ATCC 27405},
  author={Thomas Rydzak and David B Levin and Nazim Cicek and Richard Sparling},
  journal={Applied Microbiology and Biotechnology},
  year={2011},
  volume={92},
  pages={199-209}
}
When attempting to increase yields of desirable end-products during fermentation, there is the possibility that increased concentrations of one product redirects metabolism towards the synthesis of less desired products. Changes in growth, final end-product concentrations, and activities of enzymes involved in pyruvate catabolism and fermentative end-product formation were studied in Clostridium thermocellum in response to the addition of individual end-products (H2, acetate, ethanol, formate… CONTINUE READING