Encapsulation of pancreatic islets within nano-thin functional polyethylene glycol coatings for enhanced insulin secretion.

@article{Kizilel2010EncapsulationOP,
  title={Encapsulation of pancreatic islets within nano-thin functional polyethylene glycol coatings for enhanced insulin secretion.},
  author={Seda Kizilel and Andrew Scavone and Xiang Liu and J M Nothias and Diane Ostrega and Piotr Witkowski and M. Millis},
  journal={Tissue engineering. Part A},
  year={2010},
  volume={16 7},
  pages={2217-28}
}
Covalent attachment of polymers to cells and tissues could be used to solve a variety of problems associated with cellular therapies. Insulin-dependent diabetes mellitus is a disease resulting from the autoimmune destruction of the beta cells of the islets of Langerhans in the pancreas. Transplantation of islets into diabetic patients is an attractive form of treatment, provided that the islets could be protected from the host's immune system to prevent graft rejection, and smaller numbers of… CONTINUE READING