Encapsulation efficiency and controlled release characteristics of crosslinked polyacrylamide particles.

@article{Sairam2006EncapsulationEA,
  title={Encapsulation efficiency and controlled release characteristics of crosslinked polyacrylamide particles.},
  author={Malladi Sairam and Vikram Ramesh Babu and Boya Vijaya and K Lakshun Naidu and Tejraj M. Aminabhavi},
  journal={International journal of pharmaceutics},
  year={2006},
  volume={320 1-2},
  pages={
          131-6
        }
}
Polyacrylamide (pAAm) particles crosslinked with N,N-methylenebis-acrylamide/ethylene glycol dimethacrylate (NNMBA/EGDMA) have been prepared in water-methanol medium by the dispersion polymerization using poly(vinyl pyrrolidone), PVP as a steric stabilizer. 5-fluorouracil an anticancer drug, has been loaded in situ into the crosslinked pAAm particles. Plain as well as drug loaded microparticles have been characterized by differential scanning calorimetry (DSC) and X-ray diffraction studies (XRD… CONTINUE READING
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