Encapsulated dental-derived mesenchymal stem cells in an injectable and biodegradable scaffold for applications in bone tissue engineering.
@article{Moshaverinia2013EncapsulatedDM, title={Encapsulated dental-derived mesenchymal stem cells in an injectable and biodegradable scaffold for applications in bone tissue engineering.}, author={A. Moshaverinia and C. Chen and K. Akiyama and X. Xu and W. Chee and S. Schricker and S. Shi}, journal={Journal of biomedical materials research. Part A}, year={2013}, volume={101 11}, pages={ 3285-94 } }
Bone grafts are currently the major family of treatment options in modern reconstructive dentistry. As an alternative, stem cell-scaffold constructs seem to hold promise for bone tissue engineering. However, the feasibility of encapsulating dental-derived mesenchymal stem cells in scaffold biomaterials such as alginate hydrogel remains to be tested. The objectives of this study were, therefore, to: (1) develop an injectable scaffold based on oxidized alginate microbeads encapsulating… CONTINUE READING
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