Enasidenib: First Global Approval

@article{Kim2017EnasidenibFG,
  title={Enasidenib: First Global Approval},
  author={Esther S. Kim},
  journal={Drugs},
  year={2017},
  volume={77},
  pages={1705-1711}
}
  • E. Kim
  • Published 6 September 2017
  • Medicine, Biology
  • Drugs
Enasidenib (Idhifa®) is an oral isocitrate dehydrogenase-2 (IDH2) inhibitor developed by Celgene Corporation under a global, exclusive license from Agios Pharmaceuticals. Enasidenib has been approved in the USA for the treatment of adults with relapsed or refractory acute myeloid leukaemia (AML) and an IDH2 mutation as detected by an FDA-approved test. It is at various stages of development in other countries for AML, myelodysplastic syndromes and solid tumours. This article summarizes the… 
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